THE NMR CONFORMATIONAL STUDIES OF BACITRACIN A

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作者：
Xiu Weng HAN~*
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来源：
ChineseChemicalLetters | 1993年 / 05期
关键词：
THE NMR CONFORMATIONAL STUDIES OF BACITRACIN A; NMR; NOE;
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摘要：
Bacitracin consists of a mixture of several closely related polypeptide antibiotics produced from Bacillus licheniformis.The major component, Bacitracin A, is a cyclic dodecapeptide（Fig, 1）, which has strong bacteriocidal effect on the G+ bacteria. The bacteriocidal activity requires the presence of divalent cations such as Zn;, As we know, the biological function of ploypeptides and proteins are closely related to their three-dimensional structure. Bacitracin A is very important for the demonstration of the coordination site of metal and the relationship between
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页码：427 / 430
页数：4
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