The non-time-lock response(N-TLR) is regarded as an index of response topain and acupuncture in most study on unit discharge at present; the timelockresponse(TLR) is regarded as an index as well, but the meanings of NTLR andTLR are somewhat different. In the present study, the N-TLR and TLE of73 unit discharges in somatosensory cortex evoked by nociceptive stimulationof peripheral nerve (superfical peroneal or splanchnic nerve) (P-ED) wereanalysed quantitatively with micro-computer using the method of stochasticpoint process for signal analysis and compared each other. N-TLR was shownby interspike interval mean function (ISIMF); TLR was shown by normalizedcrosscovariance function (NCCVF) reflecting the relationship between stimula-tion and response.