MR dynamic Gadolinium-enhanced fast multiplanar spoiled gradient-echo and spin-echo T1-weighted fat-suppressed techniques in diagnosis of pancreatic carcinoma

Objective: To evaluate the value of MR dynamicGadolinium-enhanced fast multiplanar spoiled gradi-ent-echo (FMPSPGR) and spin-echo (SE) T1-weighted fat-suppressed techniques in the diagnosis ofpancreatic carcinoma.Methods: Eighteen cases of pancreatic carcinoma veri-fied by surgical and pathologic results were examinedby MR, and the MR sequences included SE T1WI,FSE T2WI, SE T1-weighted fat-suppressed and dy-namic Gadolinium-enhanced FMPSPGR.Results: Of 18 pancreatic carcinomas, 10, 6, and 2tumors showed respectively hypo-intensity, iso-inten-sity and hyper-intensity on SE T1WI, meanwhile, 8,6, and 4 tumors displayed hyper-intensity, iso-inten-sity and hypo-intensity on FSE T2WI in comparisonwith the normal pancreatic tissue. All of the tumorsshowed hypo-intensity on SE T1-weighted fat-sup-pressed and also obvious non-enhancement or slightenhancement on MR dynamic Gadolinium-enhancedFMPSPGR images during the arterial dominantphase scanning.Conclusion: SE T1-weighted fat-suppressed and MRdynamic Gadolinium-enhanced FMPSPGR sequencescould evidently improve the sensitivity and specificityin the diagnosis of pancreatic carcinoma.