Clinical analysis of 53 cases of struma ovarii

<正>Objective:To review the clinical characteristics of struma ovarii. Methods:Fifty-three cases of struma ovarii treated in this hospital from January 1988 to January 2008 were analyzed retrospectively,and related literatures were reviewed. Results:Struma ovarii accounted for 1.5%of ovarian teratomas diagnosed at the studied period.The mean age of onset was 39.5 years.All cases were unilateral,occurring equally in either side,with a normal contralateral ovary. Elevated serum levels of CA125(50-2265.7 U/ml) were observed in all 5 patients with ascites.There were no characteristic imaging findings and the confirmed diagnosis was dependent on histology.The management for all patients was surgery.No reoccurrence was found within mean follow-up of 58 months after operation. Conclusion:Struma ovarii is rare and occurs more often in late reproductive age,with a good prognosis.It is difficult to be diagnosed before surgery,and should be distinguished from malignant ovarian tumor.Laparoscopy is the best choice of treatment.