Synthesis and Crystal Structure of 2-Methoxy-benzoic Acid 2-Oxo-3-(2,4,6-trimethyl-phenyl)-1-oxa-spiro[4.4]non-3-en-4-yl Ester

被引：1

作者：

赵金浩 ^{[1
]}

季明华 ^{[1
,2
]}

孙雅泉 ^{[3
]}

程敬丽 ^{[1
]}

朱国念 ^{[1
]}

机构：

[1] Institute of Pesticide and Environmental Toxicology,Zhejiang University

[2] Institute of Science,Zhejiang Sci-tec University

[3] College of Chemical Engineering and Materials Science,Zhejiang University of Technology

来源：

结构化学 | 2010年 / 29卷 / 09期

基金：

中国国家自然科学基金;

关键词：

Δ3-dihydrofuran-2-one; spiromesifen; synthesis; crystal structure; biological activities;

D O I：

10.14102/j.cnki.0254-5861.2010.09.008

中图分类号：

O621.25 [];

学科分类号：

070303 ; 081704 ;

摘要：

The new title compound 2-methoxy-benzoic acid 2-oxo-3-(2,4,6-trimethyl-phenyl)-1-oxa-spiro[4.4]non-3-en-4-yl ester(3,C25H26O5) has been synthesized by the condensation reaction of 4-hydroxy-3-(2,4,6-trimethyl-phenyl)-1-oxa-spiro[4.4]non-3-en-2-one(2) with 2-methoxylben-zoyl chloride,and characterized by 1H NMR and MS spectra.Its crystal structure was determined by single-crystal X-ray diffraction.The crystal is of monoclinic,space group P21/c with a = 10.6945(7),b = 12.8176(7),c = 16.4223(10) ,β = 103.5665(17)o,V = 2188.3(2) 3,Z = 4,Dc = 1.234 g/cm3,F(000) = 864.000,μ = 0.085 mm-1,the final R = 0.0520 and wR = 0.1132 for 2732 observed reflections with I > 2σ(I).In the crystal structure,the C(1)-C(2)(1.478 ) bond is significantly shorter than the normal single C-C bond(1.53 ),suggesting that the carbonyl group on C(1) has formed a conjugated system with a double bond on C(2) and C(12).

引用

页码：1297 / 1300

页数：4

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