A novel coumarin-based water-soluble fluorescent probe for endogenously generated SO2 in living cells

被引:0
作者
Jin Yang [1 ]
Kun Li [1 ]
Ji-Ting Hou [1 ]
Chun-Yan Lu [2 ]
Ling-Ling Li [1 ]
Kang-Kang Yu [1 ]
Xiao-Qi Yu [1 ]
机构
[1] College of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education),Sichuan University
[2] Department of Radiology, West China Hospital, Sichuan University
基金
中国国家自然科学基金;
关键词
endogenously generated SO2; fluorescent probe; bioimaging;
D O I
暂无
中图分类号
O657.3 [光化学分析法(光谱分析法)]; R114 [卫生毒理];
学科分类号
070302 ; 081704 ; 100405 ;
摘要
A novel coumarin-based "turn-on" fluorescent probe SS-1 was developed for selective detection of SO;derivatives in 100% water solution among reactive sulfur species(RSS). The detection limit of the method was 91.7 nM. Moreover, the probe exhibited low cytotoxicity and was successfully applied in the imaging of endogenously generated SO;in HeLa cells.
引用
收藏
页码:793 / 798
页数:6
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