1,2,3-三唑类化合物在医药领域的研究新进展

被引:20
作者
魏金建
王艳
王宪龙
周成合
吉庆刚
机构
[1] 西南大学化学化工学院
基金
中央高校基本科研业务费专项资金资助;
关键词
1,2,3-三唑; 抗菌; 抗真菌; 抗结核; 抗病毒; 抗癌; 离子通道激活剂;
D O I
暂无
中图分类号
R96 [药理学];
学科分类号
100602 ; 100706 ;
摘要
目的综述1,2,3-三唑类化合物在医药领域的研究新进展。方法结合国内外文献阐述了1,2,3-三唑类化合物在抗微生物、抗肿瘤、离子通道激活剂等方面的研究概况。结果与讨论1,2,3-三唑类化合物作为药物的研究具有较大的开发潜力,相关研发日趋活跃。随着研究的深入,必将有众多1,2,3-三唑类化合物作为药物用于临床。
引用
收藏
页码:481 / 485
页数:5
相关论文
共 6 条
[1]  
Review on supermolecules as chemical drugs[J]. ZHOU ChengHe1,GAN LinLing2,ZHANG YiYi1,ZHANG FeiFei1,WANG GuangZhou1,JIN Lei2 & GENG RongXia1 1 School of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715,China;2 School of Pharmaceutical Sciences,Southwest University,Chongqing 400715,China.Science in China(Series B:Chemistry). 2009(04)
[2]  
Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities[J] . Xian-Long Wang,Kun Wan,Cheng-He Zhou.European Journal of Medicinal Chemistry . 2010 (10)
[3]  
Design, synthesis and bioactivity of catechin/epicatechin and 2-azetidinone derived chimeric molecules[J] . Basab Roy,Arindam Chakraborty,Sudip K. Ghosh,Amit Basak.Bioorganic & Medicinal Chemistry Letters . 2009 (24)
[4]  
Natural products in parallel synthesis: Triazole libraries of nonactic acid[J] . Sarah B. Luesse,Gregg Wells,Abhijit Nayek,Adrienne E. Smith,Brian R. Kusche,Stephen C. Bergmeier,Mark C. McMills,Nigel D. Priestley,Dennis L. Wright.Bioorganic & Medicinal Chemistry Letters . 2008 (14)
[5]  
Design and synthesis via click chemistry of 8,9-anhydroerythromycin A 6,9-hemiketal analogues with anti-MRSA and -VRE activity[J] . Akihiro Sugawara,Toshiaki Sunazuka,Tomoyasu Hirose,Kenichiro Nagai,Yukie Yamaguchi,Hideaki Hanaki,K. Barry Sharpless,Satoshi ōmura.Bioorganic & Medicinal Chemistry Letters . 2007 (22)
[6]  
1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII[J] . Vincenzo Calderone,Irene Giorgi,Oreste Livi,Enrica Martinotti,Alma Martelli,Antonio Nardi.Il Farmaco . 2005 (5)