Shoc2介导的Ras通路调控与肿瘤

[1] SUR-8, a Conserved Ras-Binding Protein with Leucine-Rich Repeats, Positively Regulates Ras-Mediated Signaling in C. elegans[J] . Derek S Sieburth,Qun Sun,Min Han. &nbspCell . 1998 (1)

[2] Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation [J]. JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (04): : 1556 - 1570

[3] The extended PP1 toolkit: designed to create specificity[J] . Mathieu Bollen,Wolfgang Peti,Michael J. Ragusa,Monique Beullens. &nbspTrends in Biochemical Sciences . 2010 (8)

[4] Prognostic relevance of LGALS3BP in human colorectal carcinoma. Piccolo E,Tinari N,D’’Addario D,et al. Journal of Translational Medicine . 2015

[5] Sur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling. Moon BS,Kim HY,Kim MY,et al. Stem Cells . 2011

[6] An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth[J] . Lucy C. Young,Nicole Hartig,Marta Mu?oz-Alegre,Juan A. Oses-Prieto,Sevi Durdu,Sabine Bender,Vineetha Vijayakumar,Matteo Vietri Rudan,Christina Gewinner,Stephen Henderson,Amit P. Jathoul,Rupinder Ghatrora,Mark F. Lythgoe,Alma L. Burlingame,Pablo Rodriguez-Viciana. &nbspMolecular Cell . 2013 (5)

[7] HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold. Jang ER,Shi P,Bryant J,et al. Molecular and Cellular Biology . 2014

[8] Functional integration of the conserved domains of Shoc2 scaffold. Jeoung M,Abdelmoti L,Jang ER,et al. Plo S one . 2013

[9] Small GTP-binding proteins. Takai Y,Sasaki T,Matozaki T. Physiological Reviews . 2001

[10] A Network of Substrates of the E3 Ubiquitin Ligases MDM2 and HUWE1 Control Apoptosis Independently of p53. Kurokawa M,Kim J,Geradts J,et al. Science Signaling . 2013

[1] SUR-8, a Conserved Ras-Binding Protein with Leucine-Rich Repeats, Positively Regulates Ras-Mediated Signaling in C. elegans[J] . Derek S Sieburth,Qun Sun,Min Han. &nbspCell . 1998 (1)

[2] Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation [J]. JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (04): : 1556 - 1570

[3] The extended PP1 toolkit: designed to create specificity[J] . Mathieu Bollen,Wolfgang Peti,Michael J. Ragusa,Monique Beullens. &nbspTrends in Biochemical Sciences . 2010 (8)

[4] Prognostic relevance of LGALS3BP in human colorectal carcinoma. Piccolo E,Tinari N,D’’Addario D,et al. Journal of Translational Medicine . 2015

[5] Sur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling. Moon BS,Kim HY,Kim MY,et al. Stem Cells . 2011

[6] An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth[J] . Lucy C. Young,Nicole Hartig,Marta Mu?oz-Alegre,Juan A. Oses-Prieto,Sevi Durdu,Sabine Bender,Vineetha Vijayakumar,Matteo Vietri Rudan,Christina Gewinner,Stephen Henderson,Amit P. Jathoul,Rupinder Ghatrora,Mark F. Lythgoe,Alma L. Burlingame,Pablo Rodriguez-Viciana. &nbspMolecular Cell . 2013 (5)

[7] HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold. Jang ER,Shi P,Bryant J,et al. Molecular and Cellular Biology . 2014

[8] Functional integration of the conserved domains of Shoc2 scaffold. Jeoung M,Abdelmoti L,Jang ER,et al. Plo S one . 2013

[9] Small GTP-binding proteins. Takai Y,Sasaki T,Matozaki T. Physiological Reviews . 2001

[10] A Network of Substrates of the E3 Ubiquitin Ligases MDM2 and HUWE1 Control Apoptosis Independently of p53. Kurokawa M,Kim J,Geradts J,et al. Science Signaling . 2013