Effects of heparin on liver fibrosis in patients with chronic hepatitis B

被引：0

作者：

Jun Shi Jing-Hua Hao Wan-Hua Ren Ju-Ren Zhu

机构：

来源：

World Journal of Gastroenterology | 2003年 / 9卷 / 07期

关键词：

in; as; cell; of; Effects of heparin on liver fibrosis in patients with chronic hepatitis B; were; on; with;

D O I：

暂无

中图分类号：

R512.62 []; R575.2 [肝硬变];

学科分类号：

1002 ; 100201 ; 100401 ;

摘要：

AIM:To evaluate the effects of heparin on liver fibrosis inpatients with chronic hepatitis B.METHODS:Fifty-two cases under study were divided intotwo groups,group A and group B.The two groups weregiven regular treatment and heparin/low molecular weightheparin (LMWH) treatment respectively.Hepatic functions,serum hyaluronic acid (HA) and type IV collagen levels weremeasured before and after the treatment,and six caseswere taken liver biopsy twice.RESULTS:After treatment,hepatic functions becamesignificantly better in both groups.Serum HA and type IVcollagen levels in group B compared with group A,decreasedsignificantly after treatment.Collagen proliferation alsodecreased in group B after treatment.CONCLUSION:Heparin/LMWH can inhibit collagenproliferation in liver tissues with hepatitis B.

引用

页码：1611 / 1614

页数：4

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