G-BANDED CHROMOSOME ANALYSES OF MUCOSAL EPITHELIUM ADJACENT TO ESOPHAGEAL CANCER (EC)——SOME CONSISTENT CHROMOSOMAL CHANGES

<正> G-banded chromosomes of primary cultures taken from mucosal epithelium adjacent to esophagealcancer (EC) were first analyzed. Consistent chromosomal changes, i. c. marker chromosomes, appeared in2 of seven specimens of esophageal epithelium. Some of the marker chromosomes are very similar to thosefound in EC8501 cell line. These results imply that the cytogenetic analyses of the mucosal epitheliumadjacent to EC may detect the numerical and structural chromosome aberrations occurring at the very be-ginning of carcinogenesis of esophageal epithelium.