Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity

被引：0
|
作者：
Juanjuan Feng [1 ]
Mingjin Rao [1 ]
Man Wang [2 ]
Lin Liang [2 ]
Zhi Chen [1 ]
Xiufeng Pang [1 ]
Weiqiang Lu [1 ]
Zhenliang Sun [2 ]
机构：
[1] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University
[2] Shanghai University of Medicine & Health Sciences Affiliated Sixth People's Hospital South Campus
来源：
Science China(Life Sciences) | 2019年 / 10期
基金：
中国国家自然科学基金;
关键词：
GLI; Triptolide suppresses pancreatic cancer cell proliferation by inhibiting hedgehog signaling pathway activity;
D O I：
暂无
中图分类号：
R285 [中药药理学]; Q25 [细胞生理学];
学科分类号：
071009 ; 090102 ; 1008 ;
摘要：
Dear Editor,Pancreatic cancer (PCa) is a high-grade gastrointestinal malignancy more commonly occurring in elderly populations with lower than 5% overall 5-year survival rate (Hidalgo, 2010). PCa responds poorly to most chemotherapeutic agents, and therefore it is imperative to develop novel therapeutic agents that have anti-cancer activities against PCa.
引用
收藏
页码：1409 / 1412
页数：4
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