microRNAs regulation and its role as biomarkers in diseases

被引：0
|
作者：
Huandi Zhou [1 ]
Xiaohui Ge [1 ]
Xiaoying Xue [1 ]
机构：
[1] Department of Radiotherapy, The Second Hospital of Hebei Medical University
来源：
Oncology and Translational Medicine | 2016年 / 2卷 / 01期
关键词：
MicroRNA; cancer; disease; drug;
D O I：
暂无
中图分类号：
R346 [];
学科分类号：
1001 ;
摘要：
Micro RNAs(miRNAs), approximately 21 to 23 nucleotides(nt) in length, belong to a set of small non-coding RNA molecules that were not thought to be functional until the recent decades. miRNAs play important roles in many diseases such as various kinds of cancers and immune disorders. Many studies have focused on the relationship between miRNAs and diseases. miRNAs are significant mediators in human growth and development and in the genesis and development of diseases. Almost 30% of the activity of protein-coding genes is forecasted to be regulated by miRNAs in mammals, and some miRNAs are regarded as potential therapeutic targets for various diseases. In this review, we outline some functions of miRNAs, especially those related to diseases.
引用
收藏
页码：39 / 46
页数：8
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