Synthesis and Expression in Escherichia coli of a Human Neutrophil Activating Protein-1/Interleukin-8 Gene

被引：0

作者：

金冬雁

徐荣辉

王平

袁劲松

侯云德

机构：

[1] NationalLaboratoryofMoleadarVirology&GeneticEngineeringChineseAcademyofPreventiveMedicine,Beijing,PRC,NationalLaboratoryofMoleadarVirology&GeneticEngineering,ChineseAcademyofPreventiveMedicine,Beijing,PRC,NationalLaboratoryofMoleadarVirology&GeneticEnginee

来源：

Progress in Natural Science Communication of State Key Laboratories of China | 1993年 / 04期

关键词：

neutrophil activating protein-1/interleukin-8; DNA synthesis; expression of cloned genes;

D O I：

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学科分类号：

摘要：

<正> Human neutrophil activating protein-1/interleukin-8 (NAP-1/IL-8)is a novel cytokineproduced mainly by monocytes and possessing the neutrophil chemotactic activity and theneutrophil activating activity.In recent years,a great deal of interest has been focused onthis protein which plays an important role in the host defense and inflammatory responsesand has the potential to be used either as an adjuvant or in the cell-specific delivery ofdrugs.The efficient expression of the NAP-1/IL-8 gene in Escherichia coli and the structur-al analysis of the recombinant NAP-1/IL-8 in solution by two-dimensional nuclear magnet-

引用

页码：369 / 373

页数：5