<正>The zymogen thrombin activable fibrinolysis inhibitor(TAFI),also known as procarboxypeptidase U(proCPU),was first described by Hendriks and coworkers in 1989.TAFI can be activated by the thrombin-thrombomodulin complex(T-TM) into its active form(TAFIa).In the activating process,Thrombin cleavesTAFI after Arg 92 resulting in the release of an amino-