Structure and Function of the NS1 Protein of Influenza A Virus

被引：0
|
作者：
Dongzi LIN~1 Jingfang LAN~2 Zhizhen ZHANG~1* 1 Department of Biochemistry and Molecular Biology
2 Department of Clinical Laboratory
机构：
来源：
Acta Biochimica et Biophysica Sinica | 2007年 / 03期
关键词：
influenza A virus; NS1A protein; RNA-binding domain; effector domain; dimer; resistance; antiviral response;
D O I：
暂无
中图分类号：
Q939.4 [病毒（滤过性病毒）];
学科分类号：
071005 ; 100705 ;
摘要：
The avian influenza A virus currently prevailing in Asia causes fatal pneumonia and multipleorgan failure in birds and humans.Despite intensive research,understanding of the characteristics of influenzaA virus that determine its virulence is incomplete.NS1A protein,a non-structural protein of influenza Avirus,was reported to contribute to its pathogenicity and virulence.NS1A protein is a multifunctionalprotein that plays a significant role in resisting the host antiviral response during the influenza infection.Thisreview briefly outlines the current knowledge on the structure and function of the NS1A protein.
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页码：155 / 162
页数：8
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