Cardioprotective and antioxidant effects of oleogum resin "Olibanum" from Boswellia carteri Birdw.(Bursearceae)

被引：0

作者：

Ahmed A. Zaki ^{[1
]}

Nadia E. Hashish ^{[1
]}

Mohamed A. Amer ^{[1
]}

Mohamed-Farid Lahloub ^{[1
]}

机构：

[1] Pharmacognosy Department, Faculty of Pharmacy, Mansoura University

来源：

Chinese Journal of Natural Medicines | 2014年 / 05期

关键词：

Boswellia carteri; Olibanum; Frankincense; Cardiovascular diseases; Antioxidant;

D O I：

暂无

中图分类号：

R965.1 [药物筛选和实验模型];

学科分类号：

100602 ; 100706 ;

摘要：

One of the leading causes of death worldwide is cardiovascular disease, hence searching for a cure is an important endeavor. The totally safe, edible, and inexpensive Boswellia plant exudate, known as olibanum or frankincense, is considered to possess diverse medicinal values in traditional medicine and from recent biological studies. Investigating the cardioprotective and antioxidant activities of olibanum from a Boswellia species, family Bursearaceae, namely Boswellia carteri Birdw. was the aim of this study. Cardioprotective activity was evaluated using a model of myocardial infarction induced by isoprenaline(ISO), while antioxidant activity was tested adopting nitric oxide scavenging(NOS) and azino-bis-3-ethyl benzthiazoline-6-sulfonic acid(ABTS) assays. The results revealed a mild cardioprotective effect and weak antioxidant activity.

引用

页码：345 / 350

页数：6

共 9 条

[1]

A Thin‐layer Chromatography Method for the Identification of Three Different Olibanum Resins (Boswellia serrata, Boswellia papyrifera and Boswellia carterii, respectively, Boswellia sacra)[J] . MichaelPaul,GeritBrüning,JochenBergmann,JohannJauch. Phytochem. Anal. . 2012 (2)

[2]

Phytochemical composition and in vitro antimicrobial and antioxidant activities of essential oils of three endemic Soqotraen Boswellia species[J] . Ramzi A.A. Mothana,Sidgi S. Hasson,Wulf Schultze,Annette Mowitz,Ulrike Lindequist. Food Chemistry . 2010 (3)

[3] Biochemical markers of myocardial injury [J].

Nigam P.K. .

Indian Journal of Clinical Biochemistry, 2007, 22 (1) :10-17

[4] Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats [J].

Sathish, V ;

Ebenezar, KK ;

Devaki, T .

PHARMACOLOGICAL RESEARCH, 2003, 48 (06) :565-570

[5]

Total antioxidant potential of resinous exudates from Heliotropium species, and a comparison of the ABTS and DPPH methods[J] . Eduardo A. Lissi,Brenda Modak,Rene Torres,Jorge Escobar,Alejandro Urzua. Free Radical Research . 1999 (6)

[6] Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture [J].

Shao, Y ;

Ho, CT ;

Chin, CK ;

Badmaev, V ;

Ma, W ;

Huang, MT .

PLANTA MEDICA, 1998, 64 (04) :328-331

[7] INHIBITION OF LEUKOTRIENE-B4 FORMATION IN RAT PERITONEAL NEUTROPHILS BY AN ETHANOLIC EXTRACT OF THE GUM RESIN EXUDATE OF BOSWELLIA-SERRATA [J].

AMMON, HPT ;

MACK, T ;

SINGH, GB ;

SAFAYHI, H .

PLANTA MEDICA, 1991, 57 (03) :203-207

[8]

Mechanisms and Consequences of Lipid Peroxidation in Biological Systems[J] . A Sevanian,P Hochstein. Annual Review of Nutrition . 1985

[9]

DERIVATIVES OF BOSWELLIC ACIDS[J] . H. Khadem,Z. El–Shafei,M. El Sekeily,M.M. Abdel Rahman. Planta Med . 1972 (06)

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