The crucial role of lysine in the hepatic metabolism of growing Holstein dairy heifers as revealed by LC-MS-based untargeted metabolomics

The objective of this experiment was to evaluate the effect of supplementing rumen-protected Lys based on a Lys-deficient diet on liver metabolism in growing Holstein heifers.The experiment was conducted for 3 months with 36 Holstein heifers(initial body weight:200±9.0 kg;7-month-old).Heifers were randomly assigned to 2 diets based on corn,soybean meal,alfalfa hay,and wheat bran:control,Lysdeficient diet(LD;0.66% Lys in diet),and Lys-adequate diet(LA;1.00% Lys in diet).The results showed no difference in growth performance between the 2 groups(P> 0.05).However,there was a clear trend of increasing feed conversion rate with Lys supplementation(0.05 更多 还原 AbstractFilter('ChDivSummary', 'ChDivSummaryMore', 'ChDivSummaryReset');