Synthesis and herbicidal activities of novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives

被引:0
作者
XU Han
Research Institute of Elemento-organic Chemistry
机构
基金
中国国家自然科学基金;
关键词
4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one; herbicidal activity; bleaching activity; synthesis;
D O I
暂无
中图分类号
O621.3 [有机合成化学];
学科分类号
070303 ; 081704 ;
摘要
Three series of forty-nine novel 4-(3-trifluoromethylphenyl)-2H-pyridazin-3-one derivatives are designed,synthesized,and evaluated through a Spirodela polyrrhiza test and a greenhouse test.Some compounds show > 80% chlorophyll inhibition of Spirodela polyrrhiza at 10 μg/mL and exhibit some herbicidal activities against Digitaria adscendens in the pre-emergence treatment at a rate of 150 g/ha.Moreover,the study of the structure-activity relationship(SAR) suggests that the appropriate bulky substituent at the right position is critical for the bleaching and herbicidal activities,which may be useful for the future design of new compounds.
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收藏
页码:157 / 166
页数:10
相关论文
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