Fluorescent antibiotics for real-time tracking of pathogenic bacteria

被引：0

作者：

Lu Miao ^{[1
]}

Weiwei Liu ^{[1
,2
]}

Qinglong Qiao ^{[1
]}

Xiaolian Li ^{[2
]}

Zhaochao Xu ^{[1
]}

机构：

[1] CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences

[2] State Key Laboratory of Fine Chemicals, Dalian University of Technology

来源：

Journal of Pharmaceutical Analysis | 2020年 / 10卷 / 05期

基金：

中国国家自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R978.1 [抗生素];

学科分类号：

100705 ;

摘要：

The harm of pathogenic bacteria to humans has promoted extensive research on physiological processes of pathogens,such as the mechanism of bacterial infection,antibiotic mode of action,and bacterial antimicrobial resistance.Most of these processes can be better investigated by timely tracking of fluorophore-derived antibiotics in living cells.In this paper,we will review the recent development of fluorescent antibiotics featuring the conjugation with various fluorophores,and focus on their applications in fluorescent imaging and real-time detection for various physiological processes of bacteria in vivo.

引用

页码：444 / 451

页数：8

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