Rh(Ⅲ)-catalyzed C8 arylation of quinoline N-oxides with arylboronic acids

被引：0

作者：

Yuanqiong Huang ^{[1
]}

Xueli Lv ^{[1
]}

Hongjian Song ^{[1
]}

Yuxiu Liu ^{[1
]}

Qingmin Wang ^{[1
,2
]}

机构：

[1] State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University

[2] Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

来源：

Chinese Chemical Letters | 2020年 / 31卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Rh~Ⅲ-catalyzed; C8; arylation; Quinoline N-oxides; Arylboronic acids; Regioselectivity;

D O I：

暂无

中图分类号：

O621.251 [];

学科分类号：

070303 ; 081704 ;

摘要：

Herein,we report the first Rh;-catalyzed regioselective C8 arylation of quinoline N-oxides with commercially available arylboronic acids as coupling partners.This procedure is simple,and the reaction shows perfect regioselectivity,a broad substrate scope,and isolated yields of up to 92%.We demonstrate the utility of the reaction by using it for late-stage functionalization of a fungicide.

引用

页码：1572 / 1575

页数：4