A Study on Protective Action of Astragalus Injection(黄芪注射液)in Ouabain-Induced Cardiac Toxicity of Guinea Pigs

被引：2

作者：

杨忠奇

冼绍祥

刘明平

陈倩维

郑惠萍

赵立诚

机构：

来源：

Chinese Journal of Integrated Traditional and Western Medicine | 2001年 / 01期

关键词：

Radix Astragalis; ouabain; cardiac toxicity;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

摘要：

Objective: To study the protective action of Astragalus Injection (AI) on ouabain induced cardiac toxicity. Methods: Forty guinea pigs were randomly divided into the AI group and the control group, AI injected intravenously in the AI group and 0.9% normal saline injected in the control group, ouabain was injected in contralateral of both groups intravenously 8 mins later. The time of cardiac ventricular tachycardia (VT) and cardiac ventricular fibrillation (VF), and the dose of ouabain were documented.Results: Compared with the control group AI could markedly prolong the time of VT and VF, and increase the dose of ouabain induces VT and VF ( P <0.01). Conclusion: AI decreases the incidence of digitalism.

引用

页码：48 / 49

页数：2