Essential concept of transplant immunology for clinical practice

被引：1

作者：

Damodar Kumbala ^{[1
]}

Rubin Zhang ^{[1
]}

机构：

[1] Section of Nephrology,Department of Medicine,Tulane University School of Medicine,New Orleans,LA 70112,United States

来源：

World Journal of Transplantation | 2013年 / 04期

关键词：

Alloimmune response; Major histocompatibility complex; Human leukocyte antigens; Co-stimulation pathway; Panel reactive antibody; Donor specific antibody; Non-human leukocyte antigens antibody; Crossmatch;

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Our understanding of transplant immunology has advanced from gross allograft rejection to cellular response and to current molecular level. More sensitive assays have been developed to characterize patient sensitization and to detect pre-existing donor-specific antibodies(DSA) in pre-transplant crossmatch. After a transplant, pre-existing or de novo DSA are increasingly monitored to guide clinical management. Therefore, it is important for clinicians to understand the basic concepts and key components of transplant immunology as well as be familiarized with the modern immunological techniques used in kidney transplantation.

引用

页码：113 / 118

页数：6

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