Role of IL-10 in the progression of kidney disease

被引：12
|
作者：
Inna Sinuani [1 ]
Ilia Beberashvili [2 ]
Zhan Averbukh [2 ]
Judith Sandbank [1 ]
机构：
[1] Pathology Department,Assaf Harofeh Medical Center,Sackler Faculty of Medicine,Tel Aviv University,Zerifin,70300,Israel
[2] Nephrology Division,Assaf Harofeh Medical Center,Sackler Faculty of Medicine,Tel Aviv University,Zerifin,70300,Israel
来源：
World Journal of Transplantation | 2013年 / 3卷 / 04期
关键词：
Transforming growth factor-β; Cystatin C; Interleukin-10; receptor; End-stage renal disease; Mesangial cell proliferation; Epithelial-to-mesenchymal transition; Allograft rejection;
D O I：
暂无
中图分类号：
R692 [肾疾病];
学科分类号：
1002 ; 100210 ;
摘要：
Interleukin-10(IL-10), a cytokine with anti-inflammatory and immunomodulatory functions, regulates the biology of B and T cells. The present review describes the role of IL-10 in normal renal physiology, during acute kidney injury and in the development of chronic renal failure. We further discuss IL-10-induced cellular and molecular pathways and their link to the progression of kidney injury.
引用
收藏
页码：91 / 98
页数：8
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