Selective aggregation of membrane proteins by membrane-mediated interactions

被引:0
|
作者
LI Shuang Yang [1 ,2 ]
ZHANG Xian Ren [2 ]
WANG Wen Chuan [2 ]
机构
[1] School of Food and Chemical Engineering, Beijing Technology and Business University
[2] State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology
基金
中国国家自然科学基金;
关键词
selective aggregation; anchored protein; transmembrane protein; dissipative particle dynamics(DPD);
D O I
暂无
中图分类号
O631.5 [聚合反应、缩聚反应]; O629.73 [蛋白质];
学科分类号
摘要
There are different types of membrane proteins in a cellular membrane,and most of them must correctly assemble into appropriate clusters for their cellular functions.In this work,we suggest a physical mechanism for selective aggregation of different membrane proteins without specific protein-protein attraction by dissipative particle dynamics method.A membrane-mediated interaction may result in different protein clusters with ideal mixing,nonideal mixing and demixing of different types of membrane proteins,depending on the extent of the similarity of membrane deformations by those proteins.
引用
收藏
页码:1683 / 1689
页数:7
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