Novel T-cell co-stimulators in cancer gene therapy and immunotherapy

被引:0
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作者
Lieping ChenBristolMyers Squibb Pharmaceutical ResearchInstitute Seattle WA USA [98121 ]
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关键词
cell; gene;
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中图分类号
R730.5 [肿瘤治疗学];
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摘要
<正> Optimal activation of T cells requires at least 2signals. Signal one is generated by interactionsbetween T cell receptor and antigenic peptide-majorhistocompatibility complex on antigen-presentingcells. Signal two is delivered by co-stimulatory ligandson antigen-presenting cells to their receptors on T
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页码:282 / 282
页数:1
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