Overview of the improvement of the ring-stage survival assay——a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum

被引：0
|
作者：
Jie Zhang [1 ]
Guo-Hua Feng [2 ]
Chun-Yan Zou [3 ]
Pin-Can Su [4 ]
Huai-E Liu [1 ,5 ]
Zhao-Qing Yang [1 ]
机构：
[1] Department of Pathogen Biology and Immunology, Kunming Medical University
[2] Biomedical Engineering Research Center, Kunming Medical University
[3] Guangxi Zhuang Autonomous Region People's Hospital
[4] Transfusion Medicine Research Department.Yunnan Kunming Blood Center
[5] Department of Infectious Diseases, The First Affiliated Hospital, Kunming Medical University
来源：
Zoological Research | 2017年 / 38卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Malaria; Artemisinin; Resistant phenotype; Ring-stage survival assay; Improvement; Application;
D O I：
暂无
中图分类号：
R531.3 [疟疾];
学科分类号：
1002 ; 100201 ;
摘要：
Artemisinin resistance in Plasmodium falciparum threatens the remarkable efficacy of artemisininbased combination therapies worldwide. Thus, greater insight into the resistance mechanism using monitoring tools is essential. The ring-stage survival assay is used for phenotyping artemisinin-resistance or decreased artemisinin sensitivity. Here, we review the progress of this measurement assay and explore its limitations and potential applications.
引用
收藏
页码：317 / 320
页数：4
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