共 34 条
Overview of the improvement of the ring-stage survival assay——a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum
被引:0
|作者:
Jie Zhang
[1
]
Guo-Hua Feng
[2
]
Chun-Yan Zou
[3
]
Pin-Can Su
[4
]
Huai-E Liu
[1
,5
]
Zhao-Qing Yang
[1
]
机构:
[1] Department of Pathogen Biology and Immunology, Kunming Medical University
[2] Biomedical Engineering Research Center, Kunming Medical University
[3] Guangxi Zhuang Autonomous Region People's Hospital
[4] Transfusion Medicine Research Department.Yunnan Kunming Blood Center
[5] Department of Infectious Diseases, The First Affiliated Hospital, Kunming Medical University
基金:
中国国家自然科学基金;
关键词:
Malaria;
Artemisinin;
Resistant phenotype;
Ring-stage survival assay;
Improvement;
Application;
D O I:
暂无
中图分类号:
R531.3 [疟疾];
学科分类号:
1002 ;
100201 ;
摘要:
Artemisinin resistance in Plasmodium falciparum threatens the remarkable efficacy of artemisininbased combination therapies worldwide. Thus, greater insight into the resistance mechanism using monitoring tools is essential. The ring-stage survival assay is used for phenotyping artemisinin-resistance or decreased artemisinin sensitivity. Here, we review the progress of this measurement assay and explore its limitations and potential applications.
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页码:317 / 320
页数:4
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