SAA、CRP联合检测在孕妇脓毒症诊断中的意义

被引:1
|
作者
范冬梅 [1 ]
李发红 [1 ]
钟丽 [1 ]
王宁 [1 ]
机构
[1] 山东省青岛市妇女儿童医院
关键词
孕产妇脓毒症; 血清淀粉样蛋白A; C反应蛋白; 联合检测;
D O I
暂无
中图分类号
R714.25 [妊娠并发症]; R446.1 [生物化学检验、临床检验];
学科分类号
100208 ; 100211 ;
摘要
目的:探讨血清淀粉样蛋白A(SAA)、C反应蛋白(CRP)在孕妇脓毒血症诊断中的价值。方法:收治脓毒血症孕妇100例及正常孕妇100例,分别检测血清SAA、CRP水平,比较SAA、CRP及SAA+CRP在诊断脓毒症中的敏感性和特异性。结果:与正常孕妇比较,脓毒症孕妇血清SAA、CRP水平均显著升高(P<0.01)。在诊断孕妇脓毒症感染中,SAA、CRP及SAA+CRP的敏感性分别为85.3%、66.67%、96.67%,特异性分别为92.8%、87.2%、94.4%。结论:血清SAA和CRP水平的检测有助于脓毒症的早期诊断及鉴别诊断,并可作为判断预后的指标。二者联合检测可提高孕妇脓毒症诊断的可靠性。
引用
收藏
页码:136 / 137
页数:2
相关论文
共 10 条
  • [1] 血清淀粉样蛋白A在疾病应用中的研究进展
    陈长强
    顾志冬
    樊绮诗
    [J]. 检验医学, 2012, (09) : 776 - 779
  • [2] 血清降钙素原测定在感染性疾病中的诊断价值
    陈鸿恩
    黄丽辉
    [J]. 检验医学与临床, 2008, (01) : 20 - 21
  • [3] The use of PCT, CRP, IL-6 and SAA in critically ill patients for an early distinction between candidemia and Gram positive/negative bacteremia[J] . Yang Fu,Jie Chen,Bei Cai,Junlong Zhang,Lixin Li. Journal of Infection . 2011 (4)
  • [4] Kinetics of c-reactive protein (CRP) and serum amyloid A protein (SAA) in patients with community-acquired pneumonia (CAP), as presented with biologic half-life times[J] . Saori Takata,Hiroo Wada,Masaki Tamura,Takashi Koide,Manabu Higaki,Shin-ichiro Mikura,Tetsuo Yasutake,Susumu Hirao,Masuo Nakamura,Koujiro Honda,Tomoko Nagatomo,Yasutaka Tanaka,Erei Sohara,Masato Watanabe,Takuma Yokoyama,Takeshi Saraya,Daisuke Kurai,Haruyuki Ishii,Hajime Goto. Biomarkers . 2011 (6)
  • [5] Obstetric intensive care unit admission: a 2-year nationwide population-based cohort study[J] . Joost J. Zwart,Just R. O. Dupuis,Annemiek Richters,Ferko ?ry,Jos Roosmalen. Intensive Care Medicine . 2010 (2)
  • [6] Rise in maternal mortality in the Netherlands
    Schutte, J. M.
    Steegers, E. A. P.
    Schuitemaker, N. W. E.
    Santema, J. G.
    de Boer, K.
    Pel, M.
    Vermeulen, G.
    Visser, W.
    van Roosmalen, J.
    [J]. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2010, 117 (04) : 399 - 406
  • [7] Establishment of an in-house ELISA and the reference range for serum amyloid A (SAA)[J] . Tsu-Lan Wu,I. Chen Tsai,Pi-Yueh Chang,Kuo-Chien Tsao,Chien-Feng Sun,Lily L. Wu,James T. Wu. Clinica Chimica Acta . 2006 (1)
  • [8] Sepsis during pregnancy[J] . Evans R. Fernández-Pérez,Salam Salman,Shanthan Pendem,J Christopher Farmer. Critical Care Medicine . 2005 (10 S)
  • [9] Incidence of severe pre‐eclampsia, postpartum haemorrhage and sepsis as a surrogate marker for severe maternal morbidity in a European population‐based study: the MOMS‐B survey[J] . Wei‐Hong Zhang,Sophie Alexander,Marie‐Hélène Bouvier‐Colle,Alison Macfarlane. BJOG: An International Journal of Obstetrics & Gy . 2004 (1)
  • [10] Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock[J] . F. M. Brunkhorst,K. Wegscheider,Z. F. Forycki,R. Brunkhorst. Intensive Care Medicine . 2000 (2)