Clinical and experimental research in antituberculosis drug-induced hepatotoxicity:a review

被引：17

作者：

Udhaya Lavinya Baskaran ^{[1
]}

Evan Prince Sabina ^{[1
]}

机构：

[1] School of Biosciences and Technology, VIT University

来源：

Journal of Integrative Medicine | 2017年 / 15卷 / 01期

关键词：

antitubercular agents; isoniazid; rifampicin; pyrazinamide; oxidative stress; complementary therapies;

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

1002 ; 100201 ;

摘要：

Drug-induced liver injury is the common adverse effect seen in patients receiving antituberculosis drugs(ATDs). There are several risk factors associated with the development of hepatotoxicity in such patients. Though there have been appreciable efforts taken by carrying out studies investigating the efficacy of several natural and synthetic compounds in minimising this effect, the only choice available for clinicians is withdrawal of drugs. This review would give a precise idea of ATD-induced hepatotoxicity,its underlying mechanisms and alternative therapies for the same.

引用

页码：27 / 36

页数：10

共 44 条

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