Endoscopic anti-reflux therapy for gastroesophageal reflux disease

被引:0
作者
Enrique Rodríguez de Santiago [1 ]
Eduardo Albéniz [2 ]
Fermin Estremera-Arevalo [2 ]
Carlos Teruel Sanchez-Vegazo [1 ]
Vicente Lorenzo-Zú?iga [3 ]
机构
[1] Department of Gastroenterology and Hepatology,Hospital Universitario Ramón y Cajal,Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS)
[2] Endoscopy Unit,Gastroenterology Department,Hospital Universitario de Navarra.Gastrointestinal Endoscopy Research Unit,Navarrabiomed Biomedical Research Center
[3] Endoscopy Unit,Gastroenterology Department,Hospital Universitari i Politècnic La Fe,Instituto de Investigación Sanitaria La Fe (IIS La Fe)
关键词
D O I
暂无
中图分类号
R655.4 [食管];
学科分类号
1002 ; 100210 ;
摘要
Gastroesophageal reflux disease has an increasing incidence and prevalence worldwide. A significant proportion of patients have a suboptimal response to proton pump inhibitors or are unwilling to take lifelong medication due to concerns about long-term adverse effects. Endoscopic anti-reflux therapies offer a minimally invasive option for patients unwilling to undergo surgical treatment or take lifelong medication. The best candidates are those with a good response to proton pump inhibitors and without a significant sliding hiatal hernia. Transoral incisionless fundoplication and nonablative radiofrequency are the techniques with the largest body of evidence and that have been tested in several randomized clinical trials. Band-assisted ligation techniques, anti-reflux mucosectomy, antireflux mucosal ablation, and new plication devices have yielded promising results in recent noncontrolled studies. Nonetheless, the role of endoscopic procedures remains controversial due to limited long-term and comparative data, and no consensus exists in current clinical guidelines. This review provides an updated summary focused on the patient selection, technical details, clinical success, and safety of current and future endoscopic anti-reflux techniques.
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页码:6601 / 6614
页数:14
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