Neuron-specific Enclose and Myelin Basic Protein in Cerebrospinal Fluid of Patients with First Episode Schizophrenia

被引：0

作者：

李淑英 ^{[1
]}

吴汉荣 ^{[2
]}

郭慧荣 ^{[3
]}

赵峥 ^{[4
]}

机构：

[1] Department of Children and Adolescent Health, Maternity and Children Health Care,Tongji Medical College, Huazhong University of Science and Technology, Wuhan ,China,Department of Psychiatry of First Affiliated Hospital of Zhengzhou University, Zhengzhou ,C

[2] Department of Children and Adolescent Health, Maternity and Children Health Care,Tongji Medical College, Huazhong University of Science and Technology, Wuhan ,China

[3] Department of Psychiatry of First Affiliated Hospital of Zhengzhou University, Zhengzhou ,China

[4] Henan Province Mental Hospital,Xinxiang ,China

来源：

华中科技大学学报(医学英德文版) | 2006年 / 02期

关键词：

schizophrenia; cerebrospinal fluid; neuron specific enolase; myelin basic protein;

D O I：

暂无

中图分类号：

R749.3 [精神分裂症];

学科分类号：

100205 ;

摘要：

In order to study whether patients with schizophrenia have cerebral injury, neuron-specific enolase (NSE) and myelin basic protein (MBP)in cerebrospinal fluid (CSF) of 33 patients with first episode schizophrenia and 9 from the control group were determined by double antibody sandwich enzyme immunoassay method. The results showed that there was significant difference in the NSE contents between the experimental group and control group (P<0.01). The NSE contents in CSF in the experimental group were positively correlated with MBP in schizophrenia patients (P<0.05). These findings suggested that patients with schizophrenia had cerebral injury.

引用

页码：228 / 230

页数：3