Bioresponsive nanogated ensemble based on structure-switchable aptamer directed assembly and disassembly of gold nanoparticles from mesoporous silica supports

被引:0
|
作者
Zhiyong Zhang [1 ]
A.Runa [1 ]
Jie Wu [1 ]
Han Zhang [1 ]
Xia Li [1 ]
Zhiqiang He [1 ]
机构
[1] Inner Mongolia Power Research Institute
关键词
Mesoporous silica; DNA aptamer; Controlled release; Bioresponsive; Nanoparticle assembly;
D O I
暂无
中图分类号
O614.123 [金Au]; TB383.1 [];
学科分类号
摘要
By taking advantage of recent advances in aptamer biology and nanotechnology, we developed a general approach for the design and fabrication of bioresponsive controlled delivery systems. It utilized the structure-switchable aptamer directed assembly and disassembly of gold nanoparticles from mesoporous silica supports, which enables the control of cargo release from the inside of the mesoporous nanoparticles specifically in the presence of target molecule.
引用
收藏
页码:779 / 782
页数:4
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