Synthesis and antitumor activity of a group ofdiosgenyl glycosides

被引:0
作者
Shu Jie Hou
机构
关键词
Diosgenyl glycosides; Glycosylation; Cytotoxicity;
D O I
暂无
中图分类号
R914 [药物化学]; R73-3 [肿瘤学实验研究];
学科分类号
100214 ; 100701 ;
摘要
Using orthogonal protection–deprotection glycosylation strategy, a series of diosgenyl glycosides with same of monosacchar- ides component but different in sequence were synthesized. The antitumor activity in vitro of synthesized diosgenyl glycosides was evaluated by standard MTT assay. It was observed that diosgenyl glycosides with a rhamnopyranosyl at C20 of glucopyranosyl residue show potent antitumor activity in vitro.
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页码:769 / 772
页数:4
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