Synthesis, Structure, and DNA Binding of a Platinum(Ⅱ) Complex Based on the 3,4,5-Trimethoxy-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline

被引：2
|
作者：
黎晓 [1 ,2 ]
罗旭健 [2 ]
杨燕 [2 ]
马利 [1 ]
王书龙 [2 ]
罗志辉 [2 ]
刘荣军 [2 ]
梁伟江 [2 ]
机构：
[1] College of Chemistry & Chemical Engineering,Chongqing University
[2] Guangxi Key Lab of Agricultural Resources Chemistry and Biotechnology,Colleges and Universities Key Laboratory for Efficient Use of Agricultural Resources in the Southeast of Guangxi,College of Chemistry and Food Science,Yulin Normal University
来源：
结构化学 | 2018年 / 37卷 / 05期
基金：
中国国家自然科学基金;
关键词：
platinum complex; DNA interaction; UV-Vis absorption;
D O I：
10.14102/j.cnki.0254-5861.2011-1812
中图分类号：
O641.4 [络合物化学（配位化学）];
学科分类号：
070304 ; 081704 ;
摘要：
A new platinum(Ⅱ) complex of [Pt(chda)(3,4,5-triopip)]Cl·2HO(1) based on 3,4,5-trimethoxy-phenyl-1 H-imidazo[4,5-f][1,10]phenanthroline(3,4,5-triopip) has been synthesized by hydrothermal methods and its consequences are characterized by elemental analysis, IR, single-crystal X-ray diffraction, UV-Vis absorption and fluorescent spectrum. The UV-Vis absorption studies reveal that the molecule undergoes considerable interaction with the nucleic acid. In this mononuclear structure, the platinum adopts a four-coordinated square planar geometry, which may favor the intercalation between the neighboring bases of the G-quadruplex(G4) DNA.
引用
收藏
页码：811 / 818
页数：8
相关论文
共 20 条
  • [1] Synthesis, Structure, and DNA Binding of a Platinum(II) Complex Based on the 3,4,5-Trimethoxy-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline
    Li Xiao
    Luo Xu-Jian
    Yang Yan
    Ma Li
    Wang Shu-Long
    Luo Zhi-Hui
    Liu Rong-Jun
    Liang Wei-Jiang
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2018, 37 (05) : 811 - 818
  • [2] Synthesis,Crystal Structure and DNA Interaction of a Chiral Platinum(Ⅱ) Complex with 2-(2,3-Dimethoxyphenyl)-1H-imidazo[4,5-f][1,10] phenanthroline
    罗旭健
    王书龙
    杨燕
    罗志辉
    刘荣军
    梁伟江
    结构化学, 2017, 36 (09) : 1486 - 1492
  • [3] Synthesis, Crystal Structure and DNA Interaction of a Chiral Platinum(II) Complex with 2-(2,3-Dimethoxyphenyl)-1H-imidazo[4,5-f][1,10] phenanthroline
    Luo Xu-Jian
    Wang Shu-Long
    Yang Yan
    Luo Zhi-Hui
    Liu Rong-Jun
    Liang Wei-Jiang
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2017, 36 (09) : 1486 - 1492
  • [4] Synthesis, characterization, and cytotoxicity of Pt (II) and Pd (II) complexes with 2-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline as ligand
    Yu, He
    Kang, Le
    Xu, Baotong
    Yao, Wei
    Fedin, Vladimir P.
    Gao, Enjun
    INORGANICA CHIMICA ACTA, 2024, 562
  • [5] Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl)imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity
    Qin, Qi-Pin
    Chen, Zhen-Feng
    Shen, Wen-Ying
    Jiang, Yan-Hua
    Cao, Dong
    Li, Yu-Lan
    Xu, Qing-Min
    Liu, Yan-Cheng
    Huang, Ke-Bin
    Liang, Hong
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 89 : 77 - 87
  • [6] Synthesis, structures and photophysical properties of four binuclear Cu(I) complexes of 1H-imidazo[4,5-f][1,10]phenanthroline
    Niu, Yan-Wen
    Liu, Xia
    Zhao, Ling
    Guo, Ya-Meng
    Li, Wen-Xin
    Ma, Miao-Miao
    Li, Xiu-Ling
    POLYHEDRON, 2019, 157 : 241 - 248
  • [7] Synthesis, Characterization, and Crystal Structure of a Chiral Platinum(II) Complex with 2-(4-Methoxy-Phenyl)-Imidazo[4, 5-f][l,10]-Phenanthroline Binding Interaction with DNA
    Luo, X. J.
    Wang, S. L.
    Xu, J. M.
    Yang, Y.
    Luo, Z. H.
    Liu, R. J.
    Liang, W. J.
    RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2017, 43 (10) : 679 - 684
  • [8] Synthesis, Characterization, and Crystal Structure of a Chiral Platinum(II) Complex with 2-(4-Methoxy-Phenyl)-Imidazo[4, 5-f][l,10]-Phenanthroline Binding Interaction with DNA
    X. J. Luo
    S. L. Wang
    J. M. Xu
    Y. Yang
    Z. H. Luo
    R. J. Liu
    W. J. Liang
    Russian Journal of Coordination Chemistry, 2017, 43 : 679 - 684
  • [9] Synthesis, structure, and DNA-binding study of a novel Zn (II) complex with fleroxacin and 1,10-phenanthroline monohydrate
    Zhu, Yujie
    Xiong, Xinnuo
    Suo, Zili
    Tang, Peixiao
    Sun, Qiaomei
    Ding, Xiaohui
    Li, Hui
    INORGANIC CHEMISTRY COMMUNICATIONS, 2019, 103 : 6 - 11
  • [10] Synthesis, Crystal Structure and DNA-Binding Property of Ag(I) Complex with 1-(3-Ethylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide
    Wu Hao
    Wang Yuan
    Zhang Ling
    Kang Rui-Fang
    Wu Wei-Na
    CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2018, 34 (06) : 1137 - 1142
12