The enhancement of stimulated Raman scattering (SRS) of acetone (C3H6O) and the generation of three color lasers in lasing dye rhodamine B (RB) were reported. The first-order Stokes wave (629.9 nm) of SRS of C3H6O was amplified by 2.83 times than that of pure C3H6O. At the same time, a dye laser of RB at the wavelength from 575 to 598 nm can be generated in a suitable concentration of RB between 3×10-5 and 2×10-4 mol/L. Thus the green pump laser, yellow dve laser, and red Stokes wave concurred.