Synthesis of bovine serum albumin imprinted Mn:ZnS quantum dots

A novel bovine serum albumin（BSA） imprinted Mn-doped ZnS quantum dots（Mn:ZnS QDs） is firstly reported.The molecular imprinted polymer（MIP） functionalized Mn:ZnS QDs（Mn:ZnS@SiO;@MIP） include the preparation of Mn:ZnS QDs,the coating of silica on the surface of Mn:ZnS QDs,and the functional polymerization by sol-gel reaction using 3-aminophenylboronic acid as the functional and cross-linking monomer in the presence of BSA（Mn:ZnS@SiO;@MIP-BSA）,and then the elution of the imprinted BSA on the surface of Mn:ZnS@SiO;QDs.The results showed that the phosphorescence of Mn:ZnS@SiO;@MIP is stronger quenched by BSA than that of non-imprinted one（Mn:ZnS@SiO;@NIP）,indicating that the selectivity of the imprinted Mn:ZnS quantum dots toward BSA is superior to that of non-imprinted one.