Inoculation with IL-2 and B7-1 co-transfected G422 murine glioblastoma cells resulting in enhanced antitumor immunity in vivo

被引：0

作者：

Yanen Lu Yizhi Yu Hong Lei Xuetao CaoDepartment of Immunology The Second Military Medical University Shanghai ^{[200433
]}

机构：

来源：

实验血液学杂志 | 1997年 / 03期

关键词：

IL; gene;

D O I：

暂无

中图分类号：

R73-36 [治疗实验];

学科分类号：

100214 ;

摘要：

<正> It's well known that interleukin-2 (IL-2) plays animportant role in eliciting antitumor immunityparticularly mediated by T cells. In addition, theexpression of MHC can be enhanced by IL-2 genetransfection in tumor cells. Recent studies have indicatedthat at least two signals are required for the activation ofnaive T cells by antigen-bearing target cells: an antigen-sopific signal and a crystimulatory signal. B7-l is an

引用

页码：300 / 300

页数：1