Selective Estrogen Receptor Modulator: Raloxifene

被引：0
作者：
Xue DAI
机构：
来源：
Journal of Reproduction and Contraception | 2011年 / 01期
关键词：
selective estrogen receptor modulator (SERM); raloxifene; estrogen agonists; estrogen antagonists;
D O I：
暂无
中图分类号：
R977.1 [激素类药物];
学科分类号：
1007 ;
摘要：
Selective estrogen receptor modulators (SERMs) are structurally different compounds that interact with intracellular estrogen receptors in target organs as estrogen receptor agonists and antagonists. Raloxifene is the only SERM approved worldwide for the prevention and treatment of postmenopausal osteoporosis. Raloxifene, which has estrogen-like actions on bone, lipids and the coagulation system, and estrogen antagonist effects on the breast and uterus, has undergone very extensive prospective, placebo-controlled, randomized trial evaluation.
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页码：51 / 60
页数：10
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