Hepatoid adenocarcinoma of the extrahepatic duct

被引：0

作者：

Yu Wang ^{[1
]}

Ying-Ying Liu ^{[1
]}

Gui-Ping Han ^{[1
]}

机构：

[1] Department of Pathology, the 2 nd Affiliated Hospital of Harbin Medical University

来源：

World Journal of Gastroenterology | 2013年 / 22期

关键词：

Extrahepatic bile ducts; Hepatocellular; Adenocarcinoma; Immunohistochemistry; Surgical pathology; Differential diagnosis;

D O I：

暂无

中图分类号：

R735.7 [肝肿瘤];

学科分类号：

100214 ;

摘要：

Hepatoid carcinoma is a unique type of extrahepatic tumor associated with hepatic differentiation and displays the morphological and functional features of hepatocellular carcinoma. Hepatoid carcinoma of the extrahepatic duct has rarely been reported in the literature. We report a 62-year-old man who presented with epigastric discomfort, xanthochromia, dull pain of the right shoulder, nausea and pruitus. Microscopic examination of the extrahepatic duct indicated that the tumor was primarily composed of "hepatoid cells", which were characterized by an eosinophilic cytoplasm, enlarged nucleus and prominent nucleoli. The cells were arranged in nests or proliferated in a trabecular pattern. Immunohistochemistry indicated that the tumor cells were positive for hepatocyte paraffin 1 and cytokeratins 8 and 18. Based on these findings, this case was diagnosed as hepatoid carcinoma of the extrahepatic duct.

引用

页码：3524 / 3527

页数：4

共 4 条

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