Analysis of Gene Expression Profile in Lung Adenosquamous Carcinoma Using cDNA Microarray

被引：0
|
作者：
YANG Fei 1
2. Department of Respiratory Medicine
机构：
来源：
Wuhan University Journal of Natural Sciences | 2004年 / 06期
关键词：
lung carcinoma; adenosquamous carcinoma; microarray; gene expression profile;
D O I：
暂无
中图分类号：
R734.2 [肺肿瘤];
学科分类号：
100214 ;
摘要：
Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4 096 human genes. Among target genes, 508 differentially expressed genes were identified in adenosquamous carcinoma of the lung, 232 genes were overexpressed and 276 genes were underexpressed. Among them, 92 genes are cell signals transduction genes, 34 genes are proto-oncogenes and tumor suppressor genes or cell cycle related genes or cell apoptosis related genes, 29 genes are cell skeleton genes, 28 genes are DNA synthesis, repair and recombination genes, 12 genes are DNA binding and transcription genes. These genes may be associated with the occurence and development of adenosquamous carinome of the lung.
引用
收藏
页码：967 / 972
页数：6
相关论文
共 50 条
  • [21] Mammary and hepatic gene expression analysis in peripartal dairy cows using a bovine cDNA microarray
    Loor, J. J.
    Dann, H. M.
    Everts, R. E.
    Rodriguez-Zas, S. L.
    Lewin, H. A.
    Drackley, J. K.
    JOURNAL OF ANIMAL SCIENCE, 2004, 82 : 196 - 196
  • [22] Mammary and hepatic gene expression analysis in peripartal dairy cows using a bovine cDNA microarray
    Loor, J. J.
    Dann, H. M.
    Everts, R. E.
    Rodriguez-Zas, S. L.
    Lewin, H. A.
    Drackley, J. K.
    JOURNAL OF DAIRY SCIENCE, 2004, 87 : 196 - 196
  • [23] An evaluation of linear RNA amplification in cDNA microarray gene expression analysis
    Zhu, BM
    Xu, F
    Baba, Y
    MOLECULAR GENETICS AND METABOLISM, 2006, 87 (01) : 71 - 79
  • [24] Identification of genes over-expressed in small cell lung carcinoma using suppression subtractive hybridization and cDNA microarray expression analysis
    Bangur, CS
    Switzer, A
    Fan, LQ
    Marton, MJ
    Meyer, MR
    Wang, TT
    ONCOGENE, 2002, 21 (23) : 3814 - 3825
  • [25] Identification of genes over-expressed in small cell lung carcinoma using suppression subtractive hybridization and cDNA microarray expression analysis
    Chaitanya S Bangur
    Ann Switzer
    Liqun Fan
    Matthew J Marton
    Michael R Meyer
    Tongtong Wang
    Oncogene, 2002, 21 : 3814 - 3825
  • [26] 95 Cases of EGFR/ALK Gene Status Analysis in Lung Adenosquamous Carcinoma
    Xu, Z.
    Xu, C.
    Wang, W.
    Xu, Q.
    Zhuang, W.
    Song, Z.
    Chen, Y.
    Chen, G.
    Fang, M.
    Lv, T.
    Song, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S2262 - S2262
  • [27] Profiling gene expression patterns of nasopharyngeal carcinoma and normal nasopharynx tissues with cDNA microarray
    He, ZW
    Ren, CP
    Xu, LG
    Liu, WD
    Xie, L
    Li, ZK
    Yao, KT
    CHINESE SCIENCE BULLETIN, 2000, 45 (09): : 830 - 834
  • [28] Profiling gene expression patterns of nasopharyngeal carcinoma and normal nasopharynx tissues with cDNA microarray
    HE Zhiwei
    Chinese Science Bulletin, 2000, (09) : 830 - 834
  • [29] Adenosquamous carcinoma of the lung (an analysis of 13 cases)
    Damadoglu, Ebru
    Aybatli, Aysun
    Yalcinsoy, Murat
    Tahaoglu, Canan
    Atasalihi, Ali
    Akkaya, Esen
    Yilmaz, Adnan
    TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX, 2005, 53 (02): : 161 - 166
  • [30] Genome - Wide expression profile of rat's vestibular nucleus responded to coriolis using cDNA microarray analysis
    Li, Ke-Shen
    Luan, Kuan
    Gu, Xue-Feng
    Dai, Da-Wei
    Zhang, Li-Wei
    Guo, Liang
    Tang, Guang
    Guo, Zhuo-Wei
    PROGRESS ON POST-GENOME TECHNOLOGIES, 2007, : 89 - 91
12345