新型冠状病毒感染相关心脏损害的机制探讨

被引：14
作者：
罗晶晶
董念国
史嘉玮
机构：
[1] 华中科技大学同济医学院附属协和医院心脏大血管外科
来源：
临床心血管病杂志 | 2020年 / 36卷 / 04期
关键词：
新型冠状病毒肺炎; 新型冠状病毒; 心脏损害; 机制;
D O I：
10.13201/j.issn.1001-1439.2020.04.001
中图分类号：
R563.1 [肺炎]; R541 [心脏疾病];
学科分类号：
1002 ; 100201 ;
摘要：
2019年12月以来,爆发于湖北省武汉市、流行于全国乃至全球的新型冠状病毒肺炎(COVID-19)引起广泛关注。其病原体被判定为一种名为SARS-CoV-2的新型冠状病毒,具有较高的传染性和致病力。SARS-CoV-2感染者除典型呼吸系统表现外,相当一部分出现心悸、胸闷等症状与心电图、心肌酶谱、心功能等改变,病毒相关心肌损伤、ACE2表达下调、炎症反应、缺氧及代谢障碍等因素与其发生发展密切相关。本文综合以往冠状病毒研究和现有COVID-19报道,对此心脏损害可能机制进行综述。
引用
收藏
页码：307 / 310
页数：4
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