NLRP3与急性痛风性关节炎相关作用研究进展

被引：5

作者：

陈昉

童娟

姚红

机构：

[1] 广州医科大学附属第一医院中医科

来源：

华南国防医学杂志 | 2014年 / 28卷 / 12期

关键词：

NLRP3; 急性痛风性关节炎; 抗炎免疫;

D O I：

暂无

中图分类号：

R589.7 [嘌呤（Purine）代谢障碍];

学科分类号：

1002 ; 100201 ;

摘要：

<正>痛风是一种单钠尿酸盐(monosodium urate,MSU)沉积所致的晶体相关性关节病,与嘌呤代谢紊乱及(或)尿酸排泄减少所致的高尿酸血症直接相关,属于代谢性风湿病范畴。主要表现为反复发作的急、慢性痛风性关节炎、痛风石、尿酸结石、尿酸性肾病等[1]。急性痛风性关节炎是一种尿酸盐在关节及关节周围组织以结晶形式沉积引起的具有自限性和以剧烈

引用

页码：1281 / 1284

页数：4

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