PROSTACYCLIN AND THROMBOXANE IN PREGNANCY-INDUCED HYPERTENSION

被引：0

作者：

Yang Chi-sun

Zhang Li-zhu

机构：

[1] DepartmentofObstetricsandGynecology

[2] ThirdHospital

[3] BeijingMedicalUniversity

[4] Beijing

来源：

CHINESEMEDICALJOURNAL | 1988年 / 12期

关键词：

D O I：

暂无

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The metabolites of prostacyclin (PGI2) and thromboxane A2 (TXA2), 6-keto-PGF1α and TXB2, of maternal plasma, umbilical vessels and placental tissue in patients with pregnancy-induced hypertension (PIH) and essential hypertension complicated by pregnancy were measured and the results compared with those in patients with normal pregnancy. The 6-keto-PGF1α contents of maternal plasma, umbilical vessels and placental tissue in patients with PIH were significantly lower than those in patients with normal pregnancy, but the TXB2 contents revealed no significant difference between the groups. The role of the two prostanoids in the pathogenesis of PIH is discussed.

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