The Anti-inflammatory Effects of CORTEX PHELLODENDRI in Acute Inflammation Animal Model

[Objective] To research on the anti-inflammatory effects of CORTEX PHELLODENDRI in acute inflammation animal model.[Methods]Two acute inflammation animal models were established,including the auricle swelling test model of mice induced by xylene,and the abdominal capillary permeability model of mice induced by 1% glacial acetic acid. The anti-inflammatory effects of CORTEX PHELLODENDRI were observed. [Results]CORTEX PHELLODENDRI had different inhibitory effects on the auricle swelling of mice induced by xylene,and the abdominal capillary permeability of mice induced by 1% glacial acetic acid. The alkaloid part had significant differences with model group(P < 0. 05 or P < 0. 01). [Conclusions]Alkaloid part had good anti-inflammatory effects; while the effects of n-butanol,ethyl acetate,chloroform and petroleum ether parts were in different degrees.