Mitogen-activated protein kinase-dependent apoptosis in norcan-tharidin-treated A375-S2 cells is proceeded by the activation of protein kinase C

被引：0
|
作者：
AN Wei-wei
机构：
来源：
中华医学杂志(英文版) | 2005年 / 03期
关键词：
norcantharidin · A375-S2 cells · mitogen-activated protein kinase · protein kinase C · staurosporine;
D O I：
暂无
中图分类号：
R73-3 [肿瘤学实验研究];
学科分类号：
100214 ;
摘要：
Background We have reported that norcantharidin (NCTD) induces human melanoma A375-S2 cell apoptosis and that the activation of caspase and the mitochondrial pathway are involved in the apoptotic process. This study aimed at investigating the roles of mitogen-activated protein kinase (MAPK) and protein kinase C (PKC) in A375-S2 cell apoptosis induced by NCTD.
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页码：23 / 28
页数：6
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