The correlation study on antimicrobial resistance and biofilm related genes in clinical isolates of Acinetobaeter baumannii

被引:0
作者
DONG Rong
GUAN Chun
HU Dan
XIN Ting-ting
QU Yan
机构
[1] Department of Intensive Care Unit,the Affiliated Qingdao Municipal Hospital Dong Yuan of Qingdao University Medical College
[2] Department of Intensive Care Unit,Linyi People’s Hospital
关键词
D O I
暂无
中图分类号
R378 [病原细菌];
学科分类号
100103 ; 100705 ;
摘要
In recent years,the proportion of nosocomial infections caused by Acinetobacter baumannff(Ab)strains has increased significantly,and its resistance to antibiotics is rising.The resistanee mechanisms of Ab are complex,which include the integron formation,inactivating or deactivating enzyme,outer membrane,permeability,biofilm formation,drug exocytosis mechanism and so on.The biofilm formation by bacteria leads to high resistance and immune evasion ability.The aim of this study is to investigate the resistance and distribution patterns of Ab isolates,and the biofilm formation related genes in Ab isolates in our hospital.
引用
收藏
相关论文
共 5 条
  • [1] The Acinetobacter baumannii 19606 OmpA Protein Plays a Role in Biofilm Formation on Abiotic Surfaces and in the Interaction of This Pathogen with Eukaryotic Cells. Jennifer A. Gaddy,Andrew P. Tomaras,Luis A. Actis. Infection and Immunity . 2009
  • [2] Isolation and Characterization of an Autoinducer Synthase from Acinetobacter baumannii. Chen Niu,Katy M. Clemmer,Robert A. Bonomo,Philip N. Rather. Journal of Bacteriology . 2008
  • [3] Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp. Anbazhagan Deepa,Mansor Marzida,Yan Gracie Ong Siok,Md Yusof Mohd Yasim,Hassan Hamimah,Sekaran Shamala Devi. PloS one . 2012
  • [4] Forging a link between biofilms and disease. Potera C. Science . 1999
  • [5] 鲍氏不动杆菌生物膜形成及相关基因研究
    魏星
    沈定霞
    罗燕萍
    曹敬荣
    [J]. 中华医院感染学杂志, 2010, 20 (18) : 2735 - 2738