Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/reperfusion injury

被引：0

作者：

Yongjun Peng

Hesheng Wang

Jianhua Sun

Li Chen

Meijuan Xu

Jihong Chu

机构：

[1] DepartmentofAcupunctureandRehabilitation,AffiliatedHospitalofNanjingUniversityofChineseMedicine

来源：

NeuralRegenerationResearch | 2012年 / 7卷 / 36期

关键词：

electroacupuncture; cerebral ischemia/reperfusion; blood-brain barrier; aquaporin-4; brain edema; rat; Renzhong (DU26); Baihui (DU20); brain injury; regeneration; neural regeneration;

D O I：

暂无

中图分类号：

R741 [神经病学];

学科分类号：

1002 ;

摘要：

This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.

引用

页码：2901 / 2906

页数：6

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