肿瘤免疫治疗不容忽视的微环境:癌相关成纤维细胞附视频

被引：5
作者：
李营歌
姚颐
宋启斌
高彦君
许斌
董熠
机构：
[1] 武汉大学人民医院
来源：
肿瘤学杂志 | 2018年 / 11期
关键词：
癌相关成纤维细胞; 肿瘤免疫; 免疫治疗; 靶向治疗;
D O I：
暂无
中图分类号：
R730.51 [免疫疗法];
学科分类号：
100214 ;
摘要：
癌相关成纤维细胞(cancer associated fibroblasts,CAF),肿瘤微环境中宿主细胞主要成分,除具有直接促瘤作用外,还可通过抑制T细胞功能、促进免疫抑制细胞功能、调节胞外基质结构参与肿瘤免疫抑制微环境的形成。抑制CAF功能和以CAF为靶点的抗肿瘤微环境治疗为免疫治疗提供新的辅助手段。
引用
收藏
页码：1060 / 1064
页数：5
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