Reorganization of spinal neural circuitry and functional recovery after spinal cord injury

被引：0

作者：

Raffaele Nardone ^{[1
,2
,3
]}

Eugen Trinka ^{[1
,2
]}

机构：

[1] Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University

[2] Spinal Cord Injury and Tissue Regeneration Center, Paracelsus Medical University

[3] Department of Neurology, Franz Tappeiner Hospital

来源：

NeuralRegenerationResearch | 2015年 / 10卷 / 02期

关键词：

SCI; Reorganization of spinal neural circuitry and functional recovery after spinal cord injury; TSR;

D O I：

暂无

中图分类号：

R651.2 [脊髓];

学科分类号：

1002 ; 100210 ;

摘要：

<正>The ability of the adult central nervous system to reorganize its circuits over time is the key to understand the functional improvement in subjects with spinal cord injury(SCI).Adaptive changes within spared neuronal circuits may occur at cortical,brainstem,or spinal cord level,both above and below a spinal lesion(Bareyre et al.,2004).At each level the reorganization is a very dynamic process,and its degree is highly variable,depending on several factors,including the age of the

引用

页码：201 / 202

页数：2

共 12 条

[1]

The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Florence M Bareyre,Martin Kerschensteiner,Olivier Raineteau,Thomas C Mettenleiter,Oliver Weinmann,Martin E Schwab. Nature Neuroscience . 2004

[2]

Bridging the gap:a reticulo-propriospinal detour bypassing an incomplete spinal cord injury. Filli L,Engmann AK,Z?rner B,Weinmann O,Moraitis T,Gullo M,Kasper H,Schneider R,Schwab ME. The Journal of Neuroscience . 2014

[3]

Trigemino-cervical-spinal reflexesafter traumatic spinal cord injury. Nardone R,H?ller Y,Orioli A,Brigo F,Christova M,Tezzon F,Golaszewski S,Trinka E. Clinical Neurophysiology . 2014

[4]

Chasingcentral nervous system plasticity:the brainstem’’s contribution to locomotor recovery in rats with spinal cord injury. Z?rner B,Bachmann LC,Filli L,Kapitza S,Gullo M,Bolliger M,StarkeyML,R?thlisberger M,Gonzenbach RR,Schwab ME. Brain . 2014

[5]

A primary acoustic startle circuit: lesion and stimulation studies. M Davis,DS Gendelman,MD Tischler,PM Gendelm. The Journal of Neuroscience . 1982

[6]

Interlimb reflexes and synaptic plasticity become evident months after human spinal cord injury. B. Calancie,M.R. Molano,J.G. Broton. Brain . 2002

[7]

Changes in spinal reflex and locomotor activity after a complete spinal cord injury: a common mechanism?. V. Dietz,S. Grillner,A. Trepp,M. Hubli,M. Bolliger. Brain . 2009

[8]

Behavior of spinal neurons deprived of supraspinal input. Volker Dietz. Nature Reviews Neurology . 2010

[9]

Interlimb reflex activity after spinal cord injury in man: strengthening response patterns are consistent with ongoing synaptic plasticity[J] . Blair Calancie,Natalia Alexeeva,James G. Broton,Maria R. Molano. &nbspClinical Neurophysiology . 2004 (1)

[10] Influence of spinal reflexes on the locomotor pattern after spinal cord injury [J].

Hubli, M. ;

Dietz, V. ;

Bolliger, M. .

GAIT & POSTURE, 2011, 34 (03) :409-414

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