Synthesis of Substituted Aziridine from (1S,2S)-2-Amino-1- (4-Nitrophenyl)- 1,3-Propanediol

被引：0
|
作者：
Yang Shao-rong1
2.College of Chemistry
机构：
来源：
Wuhan University Journal of Natural Sciences | 2000年 / 03期
关键词：
aziridines; synthesis; chloramphenicol;
D O I：
暂无
中图分类号：
O621.34 [];
学科分类号：
070303 ; 081704 ;
摘要：
S, 3R)-2-acetooxymethanyl-3-(P-nitrophenyl)-N-tosylaz iridine 5 was synthesized from (1S, 2S)-2-amino-1- (4-nitrophenyl)-1, 3-propaned iol 1 in four steps with a 24.8% overall yield. This reaction is ste reospecific and occ urs an expectable configuration inversion at α-carbon atom of benzyl group. Th e structure of substituted aziridine was determined on FT-IR, NMR, MS and so on .
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页码：345 / 347
页数：3
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